Prucalopride (Motegrity) for Chronic Idiopathic Constipation
					
					
                    
      			
            		
					
					
                
					Prucalopride (Motegrity) for Chronic Idiopathic Constipation
June 3, 2019 (Issue: 1573)
					The FDA has approved the 5-HT4 receptor agonist
prucalopride (Motegrity – Shire) for treatment of chronic
idiopathic constipation (CIC) in adults. Prucalopride is
the only drug currently approved in the US for treatment
of CIC that stimulates...more
 
        			
        			
						
	
		
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- H Piessevaux et al. A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of long-term treatment with prucalopride. Neurogastroenterol Motil 2015; 27:805. 
- R Cinca et al. Randomised clinical trial: macrogol/PEG 3350+electrolytes versus prucalopride in the treatment of chronic constipation -- a comparison in a controlled environment. Aliment Pharmacol Ther 2013; 37:876.
 
	 				
					
					
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