Treatment Guidelines from The Medical Letter
				
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ISSUE 137
    
   			
      			
      		
            		
			ISSUE 137
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				Drugs for Lipids
January 1, 2014 (Issue: 137)
				HMG-CoA reductase inhibitors (statins) inhibit
the enzyme that catalyzes the rate-limiting step in
cholesterol synthesis. The subsequent reduction in
hepatic cholesterol leads to increased expression of
LDL receptors, which in turn increases...more
        			
        			
					
					
				
        			
				The Medical Letter is a subscriber-funded nonprofit organization that publishes critical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.
				

